The Analytical Zen Podcast

The Zinc Connection: The Pancreas, Diabetes and Beyond

Geraldine M. Dowling Episode 11

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In this episode, we explore the connection between zinc and diabetes, focusing on functions of zinc in the pancreas and for blood glucose control. Using animal models of obesity and prediabetes, researchers investigated how mild zinc deficiency—similar to levels potentially seen in humans—affects the pancreas and regulation of blood glucose. The study found that a 30% reduction in pancreatic zinc led to enlarged pancreatic islets and poorer blood glucose control, especially during glucose tolerance tests. These findings highlight the significant impact even marginal zinc deficiency can have on the development and progression of type 2 diabetes. However, zinc supplements are not warranted unless someone is deficient in zinc.